Is there something wrong with my mouse?

She just started breathing oddly and jumping around the cage crazily a few minutes ago, I'm not sure what happened. I have three mice, one was sleeping in their little house, another was drinking from the water bottle and this one was sitting in the center of the cage, then she started jumping around as if she was freaking out and couldn't control it. After she stopped, I took her out of the cage and held her for a few minutes. She seems exhausted and unresponsive, I'm not sure what to do. She started to clean herself when I was holding her, but she stopped a few seconds after as if she were too tired or uninterested. Could she be having anxiety or possibly be sick?